Articles
Macrocytosis
Tags: Macrocytosis
Macrocytosis Macrocytosis refers to an increased red cell mean cell volume (MCV). The normal MCV will vary depending on the age of the patient, but in adults, is generally considered increased when it is > 100 fL. Macrocytosis is a common abnormality that is not pathological per se.
Lymphopenia
Tags: Lymphopenia
The lymphocyte reference range will vary depending on the age, gender and pregnancy status of the patient, as well as the laboratory performing the test. In general, the lymphocyte count is considered low when it is < 1.0 x109/L. Lymphopenia is a common finding and an isolated longstanding lymphopenia in adult patients, outside of intercurrent illness and without evidence of recent or active infection, is unlikely to be of clinical significance.
Lymphocytosis
Tags: Lymphocytosis , chronic lymphocytic leukemia , lymphoma
The lymphocyte reference range will vary depending on the age and gender of the patient, as well as the laboratory performing the test. In general, the lymphocyte count is considered elevated when it is above 5 x 109/L.
Iron Deficiency and Iron Deficiency Anaemia
Tags: Anaemia , Iron , Iron studies
Iron deficiency and iron deficiency anaemia are common. Australian guidelines have been published to guide the investigation and management of iron deficiency (MJA 2010; 193 (09): 525-532). Cases of iron deficiency do not require assessment in a specialist haematology department and can be managed in the community.
High Ferritin
Tags: Hyperferritinemia , ferritin , iron studies
Elevated ferritin is a common reason for referral to the haematology clinic. The vast majority of patients with elevated ferritin will not have an underlying disease which is within the scope of a haematologist. Assessment of elevated ferritin should always take into account transferrin saturation, along with a full blood count, renal and liver function tests. The algorithm below will assist in sorting out the likely cause.